Researchers develop blood test for depression & bipolar disorder

A group of researcher’s recent claims of developing a blood test for bipolar disorder and depression. The study, which has been published in Molecular Psychiatry, as to earlier research into biomarkers for tracing post-traumatic stress, suicidality disorder, and Alzheimer disease. Reports have it that the study was conducted over the course of 4 years and recruited about 300 participants.

Researchers initially observed these individuals in both low and high mood states and recorded changes in biomarkers in their blood between the 2 states. Results thus obtained were then cross-verified with huge databases from all the previous studies to enable the researchers prioritize their findings. 

As per credible reports, the study allows researchers to create a blood test sample for RNA biomarkers which has the potential to indicate the seriousness of a patient’s depression, the chances of developing severe depression in future, and risk of any upcoming bipolar disorder.

The study evaluators were then able of demonstrating how to treat patients with medications based on the tests conducted only to find out a potential medication for the treatment of depression.

Commenting on the novel accomplishment, Professor of Psychiatry at IU School of Medicine, Alexander B. Niculescu, MD, PhD, mentioned that through the progressive work, researchers wanted to develop blood tests for bipolar disorder and depression to well differentiate between the 2, and also to match people to the potential treatments.

Alexander added that the blood tests have the potential to open the door to personalized, precise matching with medication, and objective monitoring of response to treatment.

Not to mention, along with the therapeutic and diagnostic findings, the research team also concluded that mood changes are highlighted by circadian clock genes, that regulate day-nigh, sleep-wake, and seasonal cycles. This could naturally explain why certain patients face severe mood swings with seasonal changes.

Source Credit: https://www.pharmacytimes.com/view/researchers-develop-blood-test-for-depression-severity-bipolar-disorder